IJTNS International Journal of Technical and Natural Sciences IJTNS 2671-3500 2671-3519 Balkan University Press 10.69648/NDDD5147 370 Research Article Determination of Hematological and Biochemical Parameters in Blood Samples from Oncological Patients in Kosovo Dina Kushtrim Pavlova Valentina Samet Aksu Faculty of Technology and Technical Sciences, Veles, University “St. Kliment Ohridski” Bitola St. Kliment Ohridski - Bitola International Balkan University 30 06 2025 5 1 25 41 CC BY-NC-ND 4.0

Cancer is a complex disease characterized by the uncontrolled proliferation of abnormal cells, which possess the potential to invade surrounding tissues and metastasize to distant organs. Its development is influenced by a variety of factors, including genetic predisposition, environmental exposures, and individual biological characteristics. The aim of this research is to analyze the blood of 100 patients diagnosed with cancer seeking care at the University Clinical Center of Kosovo for Cancer Care, Oncology Clinic. The patients range in age from 29 to 85 years, with half being men and half being women. The blood parameters survey was conducted between January and June 2024 and was voluntary. Blood samples were tested for a total of ten hematological and biochemical parameters: hemoglobin, erythrocytes, platelets, leukocytes, iron, sedimentation, AST, ALT, urea, and creatinine. Statistical analysis of the data was conducted using the Statistical Package for Social Sciences (SPSS). Non-parametric tests were employed, including the median equality test based on the Chi-square distribution and Spearman’s rank correlation coefficient. There is a deviation from the reference values of the measured parameters in sedimentation, where the average measured value for all patients is above the upper reference limit. Namely, the sedimentation in cancer patients covered by the analysis ranges between 5 mm/h and 40 mm/h, while the average is 14.3 mm/h. Differences in median values for almost all blood parameters are also observed between patients who have metastasized disease and those in whom the disease has not metastasized. Nutritional status is a dynamic rather than a static condition. Consequently, it should be regularly evaluated throughout the various stages of the treatment process to ensure consistent and timely access to appropriate nutritional interventions.

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