<?xml version="1.0" encoding="UTF-8"?>
<article>

    <title>Determination of Hematological and Biochemical Parameters in Blood Samples from Oncological Patients in Kosovo</title>

    <slug>determination-of-hematological-and-biochemical-parameters-in-blood-samples-from-oncological-patients-in-kosovo</slug>

    
            <parent>
            <title>Volume 5, Issue 1</title>
        </parent>
    
    
            <post_type>
            <title>ARTICLES</title>
        </post_type>
    
    	
	
	<year>2025</year>

    
	<volume>5</volume>
	
    
    <content><![CDATA[<p><span class="fontstyle0">Cancer is a complex disease characterized by the uncontrolled proliferation of abnormal cells, which possess the potential to invade surrounding tissues and metastasize to distant organs. Its development is influenced by a variety of factors, including genetic predisposition, environmental exposures, and individual biological characteristics. The aim of this research is to analyze the blood of 100 patients diagnosed with cancer seeking care at the University Clinical Center of Kosovo for Cancer Care, Oncology Clinic. The patients range in age from 29 to 85 years, with half being men and half being women. The blood parameters survey was conducted between January and June 2024 and was voluntary. Blood samples were tested for a total of ten hematological and biochemical parameters: hemoglobin, erythrocytes, platelets, leukocytes, iron, sedimentation, AST, ALT, urea, and creatinine. Statistical analysis of the data was conducted using the Statistical Package for Social Sciences (SPSS). Non-parametric tests were employed, including the median equality test based on the Chi-square distribution and Spearman’s rank correlation coefficient. There is a deviation from the reference values of the measured parameters in sedimentation, where the average measured value for all patients is above the upper reference limit. Namely, the sedimentation in cancer patients covered by the analysis ranges between 5 mm/h and 40 mm/h, while the average is 14.3 mm/h. Differences in median values for almost all blood parameters are also observed between patients who have metastasized disease and those in whom the disease has not metastasized. Nutritional status is a dynamic rather than a static condition. Consequently, it should be regularly evaluated throughout the various stages of the treatment process to ensure consistent and timely access to appropriate nutritional interventions.</span></p>]]></content>

    
            <references><![CDATA[<p><span class="fontstyle0">Aziz, H. A., &amp; Habeeb, J. M. (2019). Study the effect of chemotherapy on some hematological and biochemical parameters of cancer patients in AL-Muthanna Province. Indian J PublicHealth Res Dev., 10(2), 813–816.</span></p>
<p> </p>
<p><span class="fontstyle0">Caccialanza, R., Pedrazzoli, P., Cereda, E., Gavazzi, C., Pinto, C., Paccagnella, A., Beretta, G., Nardi, M., Laviano, A ., Zagonel, V . (2016). Nutritional support in cancer patients: a position paper from the Italian Society of Medical Oncology (AIOM) and the Italian Society of Artificial Nutrition and Metabolism (SINPE). J Cancer, 7, 131–135.</span></p>
<p> </p>
<p><span class="fontstyle0">Caccialanza, R., Goldwasser, F., Marschal, O., Ottery, F., Schiefke, I., Tilleul, P., Zalcman, G., &amp; Pedrazzoli, P. (2020). Unmet needs in clinical nutrition in oncology: A multinational analysis of real-world evidence, Ther Adv Med Oncol., 12, 1-10.</span></p>
<p> </p>
<p><span class="fontstyle0">Devi, L.I., Ralte, L., &amp; Ma, A. (2006). Serum biochemical profile of breast cancer patients. Eur J Pharm Med Res., 2(6), 210–214.</span></p>
<p> </p>
<p><span class="fontstyle0">Dina, K., Pavlova, V., Tahiri, A., Kovaci, I., Blazhevska, T., Knights, V., Pavlovska Dimkovski, M., &amp; Srbinoska, M. (2024). A survey on the motivation, attitudes and frequency of use of dietary supplements in cancer patients, Journal of Hygienic Engineering and Design, 47, 121-126.</span></p>
<p> </p>
<p><span class="fontstyle0">Lodish, H., Arnold, B.S., Lawrence, Z., Paul, M., &amp; David, B.J.E. (2000). Molecular Cell Biology. 4th ed. NCBI.</span></p>
<p> </p>
<p> </p>
<p><span class="fontstyle0">Marin Caro, M.M., Laviano, A., &amp; Pichard, C. (2007). Impact of nutrition on quality of life during cancer. Curr Opin Clin Nutr Metab Care, 10, 480–487.</span></p>
<p> </p>
<p><span class="fontstyle0">MediSearch (2023). https://medisearch.io/blog/what-is-esr-level-in-cancer-patients</span></p>
<p> </p>
<p><span class="fontstyle0">Moore, D.C. (2016). Drug-induced neutropenia. Pharmacovigil Forum., 41 (12), 765–768.</span></p>
<p> </p>
<p><span class="fontstyle0">Mughal, T. I. (2004). Current and future use of hematopoietic growth factors in cancer medicine. Hematol Oncol., 22, 3,121–134.</span></p>
<p> </p>
<p><span class="fontstyle0">Muscaritoli, M., Arends, J., Bachmann, P., Baracos, V., Barthelemy, N., Bertz, H., Bozzetti, F., Hutterer, E., Isenring, E., Kaasa, S., Krznaric, Z., Laird, B., Larsson, M., Laviano, A., Muhlebach, S., Oldervoll, L., Ravasco, P., Solheim, S. T., Strasser, F., de van der Schueren, M., Preiser, J.C., &amp; Bischoff, S.C., (2021). ESPEN practical guideline: Clinical Nutrition in cancer, Clin Nutr, 40, 2898–2913.</span></p>
<p> </p>
<p><span class="fontstyle0">Network NCC. (2018). Cancer- and Induced Anemia. In: NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®), 1–51.</span></p>
<p> </p>
<p><span class="fontstyle0">Prado, C.M., Laviano, A., Gillis, C., Sung, A., Gardner, M., Yalcin, S., Dixon, S., Newman, S., Bastasch, M., Sauer, A., Hegazi, R., &amp; Chasen, M. (2022). Examining guidelines and new evidence in oncology nutrition: a position paper on gaps and opportunities in multimodal approaches to improve patient care, Support Care Cancer, 30, 3073–3083.</span></p>
<p> </p>
<p><span class="fontstyle0">Ramasamy, P., &amp; Sundaresan, S. (2016). Haematological and biochemical changes in pre and post treatment of buccal mucosa carcinoma patients, International journal of pharmaceutical science and research, 7 (7), 1000-1005.</span></p>
<p> </p>
<p><span class="fontstyle0">Senesse, P., Assenat, E., &amp; Schneider, S. (2008). Nutritional support during oncologic treatment of patients with gastrointestinal cancer: who could benefit? Cancer Treat Rev, 34, 568–575.</span></p>
<p> </p>
<p><span class="fontstyle0">Shahid, S. (2016). Critical reviews in oncology/hematology review of hematological indices of</span></p>
<p> </p>
<p><span class="fontstyle0">cancer patients receiving combined chemotherapy &amp; radiotherapy or receiving radiotherapy alone. Crit Rev Oncol Hematol. 105, 145–155.</span></p>
<p> </p>
<p><span class="fontstyle0">Shander, A., Knight, K., Thurer, R., Adamson, J., &amp; Spence, R. (2004). Prevalence and outcomes of anemia in surgery: a systematic review of the literature, Am. J. Med., 116, 7A, 58S-69S.</span></p>
<p> </p>
<p><span class="fontstyle0">Sheikh, N., &amp; Masood, M.N.N. (2014). Hematological and serological changes. J Soc Dev New Net Env. 5, 6.</span></p>
<p> </p>
<p><span class="fontstyle0">Shreya, S., Shekher, A., Puneet, P., Prasad, S. B., &amp; Buddhi Prakash Jain B. P. (2023). Haematological and biochemical analysis of blood samples from early and late stage breast cancer patients in India, Bioinformation, 19, (7), 806-809.</span></p>
<p> </p>
<p><span class="fontstyle0">Sobin, L.H., &amp; Wittekind, C. (2009). TNM Classification of Malignant Tumors. 7th ed. In Sobin LH, Gospodarowicz MK, Wittekind C, eds. Wiley-Blackwell, 1–333.</span></p>
<p> </p>
<p><span class="fontstyle0">Sonneborn-Papakostopoulos, M., Dubois, C., Mathies, V., Heß, M., Erickson, N., Ernst, T., &amp; Huebner, J. (2021). Quality of life, symptoms and dietary habits in oncology outpatients with malnutrition: a cross-sectional study, Med Oncol., 38, 1-20.</span></p>
<p> </p>
<p><span class="fontstyle0">Steele, M, &amp; Narendran, A. (2012). Mechanisms of defective erythropoiesis and anemia in pediatric acute lymphoblastic leukemia (ALL). Ann Hematol. 91(10), 1513–1518.</span></p>
<p> </p>
<p> </p>
<p> </p>
<p><span class="fontstyle3">Determination of Hematological and Biochemical Parameters in Blood Samples from Oncological Patients in Kosovo</span></p>
<p> </p>
<p><span class="fontstyle0">Uo, H. (2006). Science GS of NA and. Disaster Nursing in a Ubiquitous Society Care Package for Cancer Patients In Times of Handbook of Self-Managing. Side Effects of Chemotherapy in Times of Disaster. In: Handbook of Self-Managing Side Effects of Chemotherapy in Times of Disaster; 1–26.</span></p>
<p> </p>
<p><span class="fontstyle0">Van Cutsem, E., &amp; Arends, J. (2005). The causes and consequences of cancer-associated malnutrition, Eur J Oncol Nurs, 9, S51–S63.</span></p>
<p> </p>
<p><span class="fontstyle0">Vitaloni, M., Caccialanza, R., Ravasco, P, Carrato, A., Kapala, A., van der Schueren, M., Constantinides, D., Backman, E., Chuter, D., Santangelo, C., &amp; Maravic, Z. (2022). The impact of nutrition on the lives of patients with digestive cancers: a position paper, Supportive Care in Cancer, 30, 7991–7996.</span></p>
<p> </p>
<p><span class="fontstyle0">Wigmore, S.J., Plester, C.E., Ross, J.A., &amp; Fearon, K.C.H. (1997). Contribution of anorexia and hypermetabolism to weight loss in anicteric patients with pancreatic cancer, Br J Surg., 84, 2, 196-197.</span></p>
<p> </p>
<p><span class="fontstyle0">Wondimneh, B., Setty, S.A.D., Asfeha, G.G., Belay, E., Gebremeskel, G., &amp; Baye, G. (2019). Comparison of Hematological and Biochemical Profile Changes in Pre- and Post-Chemotherapy Treatment of Cancer Patients Attended at Ayder Comprehensive Specialized Hospital, Mekelle, Northern Ethiopia 2019: A Retrospective Cohort Study, Cancer Management and Research, 13, 625–632.</span></p>]]></references>
    
            <keywords>Cancer, Analysis, Blood, Hematology, Biochemistry</keywords>
    
    <date></date>

    <url>https://ijtns.ibupress.com/articles/determination-of-hematological-and-biochemical-parameters-in-blood-samples-from-oncological-patients-in-kosovo</url>

</article>